Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?

Late Lung Metastasis in a Patient with a Clear Cell Chondrosarcoma: An Indication for a Life-Long Follow-Up?

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Background.Clear cell chondrosarcoma (CCCS) is a rare subtype of chondrosarcoma and comprises between 1.6% click here and 2.5% of all chondrosarcoma.They are known to be chemo- and radiotherapy resistant; surgical resection is therefore the therapy of choice.

Methods.We present a 63-year-old woman with a progressive lung nodule 20 years after initial diagnosis and treatment of a clear cell chondrosarcoma of the right os naviculare.Results.On serial CT scans of the chest, an asymptomatic, slowly growing nodule in the left upper lung lobe was detected.CT-guided transthoracic biopsy of this nodule confirmed the diagnosis of here a chondrosarcoma lung metastasis.

Video-assisted thoracoscopic wedge resection was performed with complete removal of the nodule.The patient recovered well from surgery and remains in good health during further follow-up.Conclusion.Given the tendency of clear cell chondrosarcoma to recur and metastasize after extended periods of time, a long-term, possibly life-long follow-up and clinical surveillance is advisable in these patients.